Fasting Hypoglycemia: Diagnosis and Treatment
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,500
- 试验地点
- 1
- 主要终点
- Treatment Outcomes
研究概览
简要总结
Hypoglycemia is the term used to refer to lower than normal levels of blood sugar. This study will continue to research the causes of hypoglycemia.
Patients involved in the study will be admitted to the Clinical Center of the National Institutes of Health and undergo tests for evaluating blood sugar. Patients will be required to refrain from eating for a set period of time and will undergo blood tests for insulin levels and several other specific diagnostic tests related to insulin secretion. The patients will be under supervision and will be provided with appropriate medical and surgical attention as needed....
详细描述
Study Description:
The purpose of this study is to gain knowledge and experience in the diagnosis and therapy of patients with fasting hypoglycemia due to diverse etiologies, such as insulinomas. Study subjects will be evaluated and treated for their particular condition according to standard care.
Objectives:
- To understand the pathophysiology and various causes of hypoglycemia (e.g., insulinomas, MEN1, MEN2).
- To identify new circulating biomarkers of insulinomas.
- To create a repository of clinical data and samples for future research of insulinomas.
Endpoints: None
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •INCLUSION CRITERIA:
- •In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- •Male, females ages >=
- •Patients with documented fasting blood glucose below 55 mg/dl.
- •4. Patients with biochemical evidence for insulinoma or other pancreatic neuroendocrine tumors.
排除标准
- •An individual who meets any of the following criteria will be excluded from participation in this study:
- •Patients with significant cardiac disease will be excluded.
- •Subjects who are pregnant per self-report.
- •Medically unstable per the assessment of the PI.
研究组 & 干预措施
Patients with hypoglycemia
Patients with hypoglycemia due to diverse etiologies.
结局指标
主要结局
Treatment Outcomes
时间窗: every 1-3 months
resolution of hypoglycemia
次要结局
未报告次要终点