A study of Using ultrasound in the patients in icu to improve the prediction of extubation

Not yet recruiting

Registration Number: CTRI/2025/06/088176

Lead Sponsor: Racky Jose

Brief Summary: This prospective observational study demonstrates that ultrasonographic assessment of diaphragmatic parameters, particularly diaphragmatic excursion combined with the rapid shallow breathing index, serves as a reliable predictor of weaning success in ICU patients. These metrics offer superior predictive value compared to other diaphragmatic measures, such as diaphragmatic thickness fraction and time to peak inspiratory amplitude.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 50

Inclusion Criteria

)subjected to invasive mechanical ventilation for at least 24 hours.
2)suitable for spontaneous breathing trial(SBT) according to ICU protocol by the ICU doctor’s team .

Exclusion Criteria

) age more than 80 years old 2) primary diaphragmatic disease or trauma 3 undergone oesophageal and thoracic surgeries 4) pregnant women 5) electrolyte derangements and other correctable disorders 6)unstable haemodynamics.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome is successful weaning defined as no ventilator support for 48 hours post-extubation. Secondary outcomes include diaphragmatic ultrasound parameters (excursion and thickening fraction measured pre-extubation and immediately post-extubation), total ventilation duration, ICU stay, re-intubation incidence, and mortality as recorded.	no ventilator support for 48 hours post-extubation followed up

Secondary Outcome Measures

Name	Time	Method
The secondary outcomes of the study explored the association between diaphragmatic weaning parameters & the Rapid Shallow Breathing Index (RSBI). A significant correlation was found between diaphragmatic excursion & RSBI, while no significant correlation was observed between diaphragmatic thickness fraction or the time to peak inspiratory amplitude of the diaphragm & RSBI.	weaning success at 48 hours post extubation

Trial Locations

Locations (1): Goa medical college
🇮🇳
Goa, GOA, India
Goa medical college
🇮🇳Goa, GOA, India
Racky Jose
Principal investigator
7907837382
rakhi.jose07@gmail.com