Investigation on exhalation gas in patients undergoing cardiac surgery or thoracic aortic surgery using cardiopulmonary bypass

Not Applicable

• Conditions: cardiac surgery, thoracic aortic surgery

• Registration Number: JPRN-UMIN000036070
• Lead Sponsor: Division of Anesthesiology and Critical Care Medicin, Tottori University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-04
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Not provided

Exclusion Criteria

1)patients scheduled to undergo maintenance by volatile anesthesia 2)patients undergoing surgery requiring general anesthesia within 3 months prior to obtaining informed consent 3)patients with respiratory dysfunction 4)patients with severe lung disease 5)patients with smoking history within 3 months before consent acquisition 6)diabetic patients with poor control 7)patients with severe liver disease 8)patients with severe kidney disease 9)patients who receive chemotherapy, radiation therapy, immunotherapy within 3 months prior to obtaining informed consent 10)patients with systemically or locally active infections 11)highly obese patients 12)women who may be pregnant or have a possibility of pregnancy 13)patients who received study drugs or investigational drugs within 3 months prior to obtaining informed consent 14)patinets whom research investigator has determined to be inappropriate

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
change in breath concentration of various biological gases during perioperative period(and change in exhaust gas concentration of cardiopulmonary bypass if possible)

Secondary Outcome Measures

Name	Time	Method
1) relevance of breath concentration of various biological gases and blood cytokines during perioperative period 2) relevance of breath concentration of various biological gases and blood ROS during perioperative period 3) relevance of breath concentration of various biological gases and biomarkers during perioperative period 4) relevance of breath concentration of various biological gases and various inspections during perioperative period 5) relevance of breath concentration of various biological gases and respiratory function during perioperative period 6) relevance of breath concentration of various biological gases and the cardiopulmonary bypass time during perioperative period 7) relevance of breath concentration of various biological gases and surgical contents during perioperative period 8) relevance of exhaust gas concentration of cardiopulmonary bypass and manufactured products of cardiopulmonary bypass during perioperative period