Temperature and Healing in Treatment of Gingival Enlargement

Not Applicable

Completed

• Conditions: Gingival Enlargement

• Registration Number: NCT04016064
• Lead Sponsor: Tokat Gaziosmanpasa University

Brief Summary

Aim: Gingival enlargement is a common clinical condition which requires surgical approaches to alleviating these enlargement areas. The aim of this study was to investigate epithelization, gingival temperature, inflammation and pain levels in post-operative healing process in 4 different gingivectomy techniques including Er:YAG laser, Nd:YAG laser, electrosurgery and conventional gingivectomy in treatment of chronic inflammatory gingival enlargements.

Material and Method: A split-mouth designed study was conducted on 37 systemically healthy patients consisting of 19 females and 18 males, who had gingival enlargement areas on the left and right of maxillary and mandibular anterior regions. Gingival crevicular fluid (GCF) samples were collected, clinical periodontal parameters and gingival temperature levels were recorded at baseline and in the postoperative period. The gingival temperature was measured during surgical procedures. Gingival temperature and epithelization levels in 3rd, 7th, 10th and 15th days; GCF levels in 15th, 30th, and 90th days and pain levels in 2nd and 8th hours and between 1st-7th days of post-operative healing process were evaluated.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01-01
• Primary Completion: 2013-05-01
• Study Completion: 2013-12-01
• Status Verified: 2019-07
• Study First Submitted: 2019-07-08
• Study First Submitted QC: 2019-07-10
• Last Update Submitted: 2019-07-10
• Study First Posted: 2019-07-11
• Last Update Posted: 2019-07-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• systemically healthy individuals
• the existence of at least 20 functioning teeth, the existence of chronic inflammatory gingival enlargement in anterior quadrants.

Exclusion Criteria

• pregnancy/lactation
• drug use, previous periodontal therapy within 6 months
• previous antibiotic use within 6 months, smoking
• the existence of attachment/bone loss. .

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Epithelization	Epithelization was evaluated at postoperative 7th day	Wound surface epithelization in the healing process was evaluated with a staining solution (Mira-2-tone, GMBH \& Co., Duisburg, Germany). (O. Ozcelik et al., 2008)

Secondary Outcome Measures

Name	Time	Method
Gingival temperature	The gingival temperature was measured during surgical procedures	The temperature measurement during the process was performed by an infrared thermometer (Optris GMBH, Manuel LS, Berlin, Germany). The device had a measurement and recording range from -35 ° C to 900 ° C, optical resolution 75: 1, thermal resolution 0.1 ° C, waveband range 8-14, USB interface and graphical software program.

Trial Locations

Locations (1)

Gaziosmanpasa University; 🇹🇷 Tokat, Turkey