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临床试验/NCT06442969
NCT06442969已完成不适用

Implementing an Intervention to Reduce Heat Stress and Chemical Exposures

San Diego State University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年6月7日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1
主要终点
Participant hydration level

研究概览

简要总结

The investigators are studying the dangers that farmworkers face while working in the fields and at home. The investigators goals are:

  1. Measure how much heat and chemicals farmworkers in Imperial County are exposed to.

The investigators will ask the participants to wear a special belt under their clothes during work to measure heat. The investigators will also put two small temperature monitors in the participant's home for a day. The investigators will collect a urine sample to check hydration, and also measure the participants height, weight, blood pressure, and some blood markers for diseases using a simple finger-prick test.

To measure chemicals, the investigators will give the participants a wristband to wear for a week and hang another in the participants home. The investigators will also collect dust from each participant's home with a vacuum. Then, the investigators will analyze everything at San Diego State University.

After collecting samples, a trained community health worker will ask the participants a few questions about their work, lifestyle, health symptoms, and any hazards they face. The investigators will meet the participants twice at their homes to distribute the tools which will later be collected. Once the tools are collected, the investigators will have the chance to follow up with the participants if they have any questions. 2. Provide help to lower heat and chemical exposure with the help of community health workers. 3. Measure heat and chemicals again using the same methods to see if the project made a difference. 4. Talk to participants about what they liked and how the investigators can make future projects better.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Currently living in Imperial County, California, USA
  • Currently work in agriculture
  • Plan on living in Imperial Valley for the next 6 months

排除标准

  • Not currently living in Imperial County, California, USA
  • Not currently working in agriculture
  • Not planning to live in Imperial Valley for the next 6 months

研究组 & 干预措施

All participants

Other

All participants will receive the intervention

干预措施: Education and resources provided by community health workers (Other)

结局指标

主要结局

Participant hydration level

时间窗: Assessment at baseline (pre-intervention) and again immediately (week) after the intervention

Specific gravity of participant's urine

Concentration of chemicals measured in silicon wristbands hung in the participant's household.

时间窗: Assessment at baseline (pre-intervention) and again immediately (week) after the intervention

Silicon wristbands will be hung in participants' homes twice; once at baseline and again after the intervention. The research team will collect the wristbands and transport them to San Diego State University for analysis of different classes of chemicals, including pesticides, organophosphates, pyrethroids, and legacy pollutants. The chemicals adhered to the wristbands will be extracted in ethyl acetate and then passed through a solid-phase extraction. Extracts will be analyzed using a two-dimensional gas chromatography coupled to time-of-flight mass spectrometry at San Diego State University. The final concentration of each chemical will be expressed as nanograms per gram of wristband.

Individual heat stress

时间窗: Assessment at baseline (pre-intervention) and again immediately (week) after the intervention

Skin temperature in degrees Celsius derived from skin temperature monitor worn against the participant's skin.

Concentration of chemicals measured in silicon wristband worn by study participant

时间窗: Assessment at baseline (pre-intervention) and again immediately (week) after the intervention

Participants will be asked to wear a silicon wristbands twice; once at baseline and again after the intervention. The research team will collect the wristbands and transport them to San Diego State University for analysis of different classes of chemicals, including pesticides, organophosphates, pyrethroids, and legacy pollutants. The chemicals adhered to the wristbands will be extracted in ethyl acetate and then passed through a solid-phase extraction. Extracts will be analyzed using a two-dimensional gas chromatography coupled to time-of-flight mass spectrometry at San Diego State University. The final concentration of each chemical will be expressed as nanograms per gram of wristband.

Concentration of chemicals measured in participant's household dust collected with a vacuum

时间窗: Assessment at baseline (pre-intervention) and again immediately (week) after the intervention

The research team will visit the participant's home twice to collect the dust samples of the living area using a vacuum; once at baseline and again after the intervention. After collection, the research team will transport the dust samples to San Diego State University to measure the concentrations of different classes of chemicals, including pesticides, organophosphates, pyrethroids, and legacy pollutants. The chemicals in the dust will be extracted in ethyl acetate and then passed through a solid-phase extraction. Extracts will be analyzed using a two-dimensional gas chromatography coupled to time-of-flight mass spectrometry at San Diego State University. The final concentration of each chemical will be expressed as nanograms per gram of dust.

Participant household temperature

时间窗: Assessment at baseline (pre-intervention) and again immediately (week) after the intervention

Household temperature in degrees Celsius, derived from weather monitor placed in the participant's home.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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