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Clinical Trials/NCT04602858
NCT04602858
Completed
N/A

Reactive Balance Training Involving Repeated Trips and Slips in Older Adults: Mechanisms and Long-term Retention

Neuroscience Research Australia1 site in 1 country118 target enrollmentDecember 1, 2020
ConditionsFallFall Injury

Overview

Phase
N/A
Intervention
Not specified
Conditions
Fall
Sponsor
Neuroscience Research Australia
Enrollment
118
Locations
1
Primary Endpoint
Laboratory induced falls
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Falls in older people are devastating, widespread, costly and increasing in the aging Australian population. Although falls occur in approximately one third of older adults, certain population groups such as the sarcopenic/frail present with further elevated risk of falls. Many exercise interventions have been trialled but systematic review evidence indicates such programs reduce fall rates by an average of only 20% and encounter issues such as compliance.

Reactive balance training (also called perturbation-based balance training) utilises a task-specific approach to balance training, applying repeated exposure to unpredictable perturbations that mimic balance disturbances experienced in daily life. Evidence suggests 50% reductions in falls might be achievable in a time efficient manner with reactive balance training but more evidence is required.

In this study, ecologically valid, unpredictable trips and slips will be exposed to older people in a safe environment to train their reactive balance. Three 40 min weekly training sessions will be followed by 3-monthly retraining session over one year (40 min x 6 training sessions = 4 hours of training in total). The neuromuscular, physiological, psychological, behavioural effects of the reactive balance training will be comprehensively examined.

Registry
clinicaltrials.gov
Start Date
December 1, 2020
End Date
November 19, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Older persons - aged 65 years and older
  • Community-dwelling
  • Ability to walk 500m without rest or use of mobility aids

Exclusion Criteria

  • Diagnosed neurological disease - eg Parkinson's disease, multiple sclerosis
  • Cognitive impairment and dementia
  • Bone fractures or joint replacement (in the past year)
  • Pre-existing medical conditions from which the medical practitioner has advised not to exercise

Outcomes

Primary Outcomes

Laboratory induced falls

Time Frame: 12 month re-assessment

Fall incidence after slips and trips in the laboratory (Okubo et al., 2019). A fall will be defined by the harness supported load when it exceeded 30% of the person's body weight (Yang et al., 2011).

Slips in daily life

Time Frame: Throughout a follow-up period (one year from randomisation)

Number of slips in daily life will be recorded using a fridge calendar and reported weekly via SMS or email.

Trips in daily life

Time Frame: Throughout a follow-up period (one year from randomisation)

Number of trips in daily life will be recorded using a fridge calendar and reported weekly via SMS or email.

Secondary Outcomes

  • Margin of stability(12 month re-assessment)
  • Fear of falling(12 month re-assessment)
  • Fall Behavioural Scale(12 month re-assessment)
  • Catch-inhibition accuracy(12 month re-assessment)
  • Falls in daily life(Throughout a follow-up period (one year from randomisation))
  • Anxiety(12 month re-assessment)
  • Muscle activation amplitude (semitendinosus)(12 month re-assessment)
  • Fall Risk(12 month re-assessment)
  • Volitional Stepping Reaction time(12 month re-assessment)
  • Stepping inhibition(12 month re-assessment)
  • Executive function(12 month re-assessment)
  • Extrapolated centre of mass(12 month re-assessment)
  • Fall risk awareness and behaviours(Month 6 (middle of the follow-up period))
  • Physical activity levels(12 month re-assessment)
  • Range of trunk sway(12 month re-assessment)
  • Muscle activation onset latency (semitendinosus)(12 month re-assessment)
  • Muscle activation amplitude (rectus femoris)(12 month re-assessment)
  • Step length(12 month re-assessment)
  • Muscle activation onset latency (rectus femoris)(12 month re-assessment)
  • Adverse events during reactive balance training(Throughout training sessions taking place at week 1, 2 and 3, and month 3, 6 and 9)
  • Enjoyment of reactive balance training(Throughout training sessions taking place at week 1, 2 and 3, and month 3, 6 and 9)

Study Sites (1)

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