Single-center Ambispective Observational Study on the Role of Magnetic Resonance Imaging (MRI) in the Evaluation of Patient Affected by Hepatic Metastases of Carcinoma of the Colorectal Cancer (CRC).
Recruiting
- Conditions
- Colorectal Cancer
- Interventions
- Radiation: Hepatic MRI
- Registration Number
- NCT05950503
- Brief Summary
This study wants to evaluate the use of MRI in the managemente of mCRC with liver only metastases.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Age > 18 years;
- Histological diagnosis of colorectal cancer;
- Presence of liver metastases in the staging exams (chest-abdomen CT with contrast medium or PET-CT with 18-FDG);
- At least one measurable liver lesion according to RECIST 1.1 criteria;
- Adequate organ and marrow function.
Exclusion Criteria
- Age < 18 years;
- Inability to undergo MRI;
- Major contraindications to liver surgery;
- No written informed consent.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description mCRC patients Hepatic MRI Patients with mCRC with liver-only metastases
- Primary Outcome Measures
Name Time Method Surgery conversion rates 3 years Negative conversion rate is: patients initially considered operable and subsequently not considered suitable for surgery compared to the total number of patients enrolled.
Positive conversion rate is: patients initially deemed ineligible for surgery and subsequently operated, compared to the total number of patients enrolled.
- Secondary Outcome Measures
Name Time Method Overall survival 3 years Time from enrollment to death
Trial Locations
- Locations (1)
Policlinico Agostino Gemelli
🇮🇹Roma, Italy