Does the treatment of maternal Attention Deficit Hyperactivity Disorder enhance the effectiveness of parent management training for children's attention deficit hyperactivity disorder?

Not Applicable

Completed

• Conditions: Attention Deficit Hyperactivity Disorder (ADHD) in children and their mothers; Mental and Behavioural Disorders; Hyperkinetic disorders

• Registration Number: ISRCTN73911400
• Lead Sponsor: Wuerzburg University Hospital (Germany)

Brief Summary

1. 2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/23070786 2. 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/26123832 3. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/30545333

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-03-29
• Study Completion: 2009-12-31
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 144

Inclusion Criteria

All patients:
1. Voluntary and written informed consent of the mother, the child and other persons having the care and custody of the child

Children:
1. Aged six to 12 years
2. Diagnosis of ADHD according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria
3. No medication or on stable medication for at least four weeks before baseline assessment

Mothers:
1. Diagnosis of ADHD according to DSM-IV criteria
2. A score of 30 or more on the short version of the Wender-Utah-Rating-Scale
3. Aged 18 to 60 years, inclusive
4. Chronic course of ADHD symptoms from childhood to adulthood, onset of ADHD symptoms before the age of seven
5. No abnormality detected on physical examination, routine blood testing (blood count, renal, hepatic and thyroid function), Electrocardiogram (ECG) and Electroencephalogram (EEG)

Exclusion Criteria

All patients:
1. Participation in another clinical trial
2. Specific interventions for the treatment of ADHD within the last six months before screening
3. Need for inpatient treatment

Children:
1. Intelligence Quotient (IQ) less than 80
2. Pervasive developmental disorder, psychosis, schizophrenia, bipolar disorder, severe depressive episode

Mothers:
1. IQ less than 80
2. Schizophrenia, bipolar disorder, borderline personality disorder, antisocial personality disorder, suicidal or self-injurious behaviour, autism, motor tics, Tourette's syndrome
3. Substance abuse/dependence within six months prior to screening. Episodic abuse is not an exclusion criterion
4. Neurological diseases, seizures, glaucoma, uncontrolled hypertension
5. Current eating disorder/low weight (Body Mass Index [BMI] less than 20)
6. Pregnancy or breast-feeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified