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SEATTLE CHILDREN'S HOSPITAL

SEATTLE CHILDREN'S HOSPITAL logo
πŸ‡ΊπŸ‡ΈUnited States
Ownership
Private, Subsidiary
Employees
-
Market Cap
-
Website
http://www.seattlechildrens.org/research

Clinical Trials

202

Active:15
Completed:115

Trial Phases

6 Phases

Early Phase 1:1
Phase 1:34
Phase 2:9
+3 more phases

Drug Approvals

1

FDA:1

Drug Approvals

Oxygen

Approval Date
Nov 6, 2023
FDA

Clinical Trials

Distribution across different clinical trial phases (184 trials with phase data)β€’ Click on a phase to view related trials

Not Applicable
128 (69.6%)
Phase 1
34 (18.5%)
Phase 2
9 (4.9%)
Phase 3
6 (3.3%)
Phase 4
6 (3.3%)
Early Phase 1
1 (0.5%)

Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors

Not Applicable
Not yet recruiting
Conditions
Solid Tumor (Excluding CNS)
Hepatocellular Carcinoma
Liver Cell Carcinoma
Liposarcoma
Yolk Sac Tumor
Rhabdomyosarcoma
Interventions
Biological: SC-CAR.GPC3xIL15.21 CAR T cells
First Posted Date
2025-11-04
Last Posted Date
2025-11-04
Lead Sponsor
Seattle Children's Hospital
Target Recruit Count
21
Registration Number
NCT07224568
Locations
πŸ‡ΊπŸ‡Έ

Fred Hutch Cancer Center, Seattle, Washington, United States

Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

Not Applicable
Not yet recruiting
Conditions
Solid Tumor (Excluding CNS)
Liver Cell Carcinoma
Malignant Rhabdoid Tumor
Yolk Sac Tumor
Liposarcoma
Rhabdomyosarcoma
Embryonal Sarcoma of Liver
Wilms Tumor
Hepatocellular Carcinoma
Hepatoblastoma
Interventions
Biological: SC-CAR.GPC3xIL15.21 CAR T cells
First Posted Date
2025-08-29
Last Posted Date
2025-08-29
Lead Sponsor
Seattle Children's Hospital
Target Recruit Count
21
Registration Number
NCT07148050
Locations
πŸ‡ΊπŸ‡Έ

Seattle Children's Hospital, Seattle, Washington, United States

Concussion Recovery and Support Program

Not Applicable
Recruiting
Conditions
Brain Concussion
Mild Traumatic Brain Injury
Headache
First Posted Date
2025-07-31
Last Posted Date
2025-10-20
Lead Sponsor
Seattle Children's Hospital
Target Recruit Count
40
Registration Number
NCT07097792
Locations
πŸ‡ΊπŸ‡Έ

Seattle Children's Research Institute, Seattle, Washington, United States

πŸ‡ΊπŸ‡Έ

University of Washington, Seattle, Washington, United States

Feasibility and Acceptability of the Technology Based Enhanced Gender Support Platform Implementation With Parents

Not Applicable
Not yet recruiting
Conditions
Parents
Usability
First Posted Date
2025-06-15
Last Posted Date
2025-06-24
Lead Sponsor
Seattle Children's Hospital
Target Recruit Count
36
Registration Number
NCT07022392
Locations
πŸ‡ΊπŸ‡Έ

Seattle Children's Hospital, Seattle, Washington, United States

Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

Not Applicable
Recruiting
Conditions
Diabetes Mellitus Type 2
First Posted Date
2025-04-20
Last Posted Date
2025-06-13
Lead Sponsor
Seattle Children's Hospital
Target Recruit Count
90
Registration Number
NCT06936670
Locations
πŸ‡ΊπŸ‡Έ

Seattle Children's Hospital, Seattle, Washington, United States

πŸ‡ΊπŸ‡Έ

University of Washington Medicine Diabetes Institute, Seattle, Washington, United States

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News

Blinatumomab Combination Therapy Wins Prestigious Trial of the Year Award for Pediatric Leukemia Breakthrough

The Children's Oncology Group AALL1731 trial received the David Sackett Trial of the Year Award for demonstrating that adding blinatumomab to chemotherapy reduces relapse risk by about two-thirds in children with B-cell acute lymphoblastic leukemia.

B7-H3 CAR T-Cell Therapy Shows Promise in Diffuse Intrinsic Pontine Glioma

A phase I clinical trial demonstrates the feasibility and tolerability of repeated intraventricular B7-H3 CAR T-cell infusions in children with DIPG.

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