The effect of Cynara Scolymus on hyperlipidemia

Phase 2

• Conditions: Chronic kidney disease.; Kidney damage with moderately decreased GFR (30-59 mL/min); Kidney damage with severely decreased GFR (15-29 mL/min); Chronic uraemia End stage kidney disease: in allograft failure NOS on dialysis or without dialysis or transplant , Renal retinitis ,; N18.5 ,N18

• Registration Number: IRCT2016021622689N3
• Lead Sponsor: Vice chancellor for research and technology, Tehran university of medical sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Entry criteria:Patients with chronic kidney disease, stage 3 (GFR: 30-59 mL/min/1.73m2); stage 4 (GFR: 15-29 mL/min/1.73m2); stage 5 (GFR< 15 ml/min/1.73 m 2 ); with failure to control blood lipids (serum LDL =110 mg/dl & cholestrol = 200); without exclusion criteria; also willing to participate in the study; and at least 4 months before the start of the study have received low-fat diet and statin drugs; having a case in considered nephrology center; The willingness of patients to participate in research
??Exclusion criteria: History of biliary obstructive disorders and gallstones; Artichoke use at least one month before the start of the study; unwillingness to continue to cooperate or traveling or death; pregnancy and lactation; the development of side effects of drug; lack of medication over a week.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum LDL concentration. Timepoint: At baseline and at the end of 4 and 8 weeks of study. Method of measurement: Special kits.