The effect of vitamin C on stress intensity in long-term fasting

Phase 3

Recruiting

• Conditions: Stress responses in prolonged preoperative fasting In abdominal hysterectomy surgery.; Reaction to severe stress, and adjustment disorders

• Registration Number: IRCT20130814014359N5
• Lead Sponsor: Rasht University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 February 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Patients, candidate for elective abdominal hysterectomy
Age between 35-65
Fasting time, more than 12 hours

Exclusion Criteria

Patient dissatisfaction
Hysterectomy in malignancy
Accompanying surgery
Patients under treatment with steroids, including inflammatory and rheumatic diseases
endometriosis
Diabetes type one and two
Pelvic inflammatory diseases
transfusion during surgery

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in CRP factor levels in blood. Timepoint: Prior to infusion of vitamin C, 24 and 48 hours after surgery. Method of measurement: Taking blood sample.;Changes glucose levels in blood. Timepoint: Prior to infusion of vitamin C, 24 and 48 hours after surgery. Method of measurement: Taking blood sample.

Secondary Outcome Measures

Name	Time	Method
Systolic and diastolic blood pressure changes. Timepoint: Prior to infusion of vitamin C, 24, 48 hours after surgery. Method of measurement: Measuring the patient's blood pressure.;Changes in heart rate. Timepoint: Prior to infusion of vitamin C, 24, 48 hours after surgery. Method of measurement: Getting the patient's pulse.;Duration of staying in the hospital. Timepoint: discharge day. Method of measurement: Number of days in hospital.