The effect of topical vitamin K on skin rash
- Conditions
- Skin rash.Rash and other nonspecific skin eruption
- Registration Number
- IRCT20150304021338N3
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 48
Patients with metastatic colorectal cancer that are candidates for treatment with Cetuximab .
Patients with grade 1 to 4 skin lesions, after using Cetuximab(based on Common Terminology Criteria for Adverse Events4 (CTCAE4))
Be over 18 years old
The patient should not undergo radiotherapy.
Have a desire to participate in the study.
The patient has skin lesions before receiving cetuximab (including rash, acne, pustules, inflammatory erythema)
Being pregnant or in breastfeeding duration
Previous history of allergies to compounds containing vitamin K
Has a psychiatric disorder that is not able to participate in the study
For other reasons, he is taking drugs that have a drug interaction with topical vitamin K
Be taking medicinal compounds containing vitamin K
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Grade of skin lesions, based on Common Terminology Criteria for Adverse Events4 (CTCAE4). Timepoint: At the beginning of the study and 4 and 8 weeks after using topical vitamin K. Method of measurement: Based on CTCEA4.
- Secondary Outcome Measures
Name Time Method