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Effect of injection zoledronic acid given directly into the giant cell tumour of bone

Phase 2
Conditions
Health Condition 1: D169- Benign neoplasm of bone and articular cartilage, unspecified
Registration Number
CTRI/2024/01/062092
Lead Sponsor
All India Institute of Medical Sciences , Rishikesh
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. All the patients of biopsy proven GCT with aggressiveness on radiology (campanacci

grade 3) will be included

2. Patient who consents for the study

3. Male or female > 18 years of age

4. Histologically proven GCT of axial and appendicular skeleton

5. Recurrent GCT

6. Pathological fracture in GCT

7. Patient with normal renal function test and serum calcium levels

8. Patients who comply with adequate follow-up

Exclusion Criteria

? Other previous malignancy within 5 years, with exception of a history of a previous

basal cell carcinoma of the skin or pre-invasive carcinoma of the cervix

? Known hypersensitivity reaction to drug used

? Pregnancy or lactating

? Medical or psychological condition which in the opinion of the investigator would not

permit the patient to complete the study or sign meaningful informed consent

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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