NL-OMON48436
Completed
Not Applicable
Quantitative MRI of extra-ocular muscles in myasthenia gravis - Quantitative MRI of extra-ocular muscles in myasthenia gravis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- eids Universitair Medisch Centrum
- Enrollment
- 89
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Trial is onging in other countries
Investigators
Eligibility Criteria
Inclusion Criteria
- •Recently diagnosed MG patients
- •\- Definitive diagnosis of MG defined as the presence of serum autoantibodies
- •(anti\-acetylcholine receptor \[AChR], anti\-muscle specific tyrosine kinase
- •\- Start of symptoms was less than a year ago
- •\- No corticosteroid treatment received in the past year
- •\- No TSH\-receptor auto\-antibodies, no laboratory signs of thyroid dysfunction
- •(T4, TSH), Chronic MG patients
- •\- Definitive diagnosis of MG, defined as described above
- •\- Persisting symptoms of diplopia
- •\- Start of symptoms was more than a year ago
Exclusion Criteria
- •\- Subjects who are not legally capable
- •\- Subjects under the age of 18
- •\- Contraindications to MRI scanning, including:
- •o Claustrophobia
- •o Pregnancy
- •o Pacemakers and defibrillators
- •o Nerve stimulators
- •o Intracranial clips
- •o Metallic fragments
- •o Cochlear implants
Outcomes
Primary Outcomes
Not specified
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