Comparison of the efficacy of 0.5 percent levobupivacaine versus 0.75 percent ropivacaine in ultrasound guided costoclavicular block for upper limb surgeries - A prospective randomized control study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess the mean duration of sensory block between the two groups
研究概览
简要总结
Costoclavicular approach is a modification of the infraclavicular brachial plexus block, It’s a novel and upcoming ultrasound technique with known reliable analgesia, compact anatomy and higher patient safety. Ropivacaine and levobupivacaine are being widely used due to their long duration of action and higher safety profile. Their action in the costoclavicular approach has not been studied yet. We hypothesize that they will have equal mean duration of analgesic action but ropivacaine with a higher sensory propensity will show early motor regression and is more advantageous for early post operative rehabilitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age between 18 and 65 years ASA physical status 1 and 2 and 3 Voluntary participation in the trial Surgeries for upper limb below mid shaft of humerus under brachial plexus block.
排除标准
- •Refusal to participate Local anesthetic allergy Infection at block site Prior infraclavicular fossa surgery Bleeding or evidence of coagulopathy.
结局指标
主要结局
To assess the mean duration of sensory block between the two groups
时间窗: 2, 4, 6, 8, 10 , 12 hours post operatively
次要结局
- onset of sensory block(0, 5, 10, 15, 20, 25 and 30 mins after injection)
- onset of motor block(0, 5, 10, 15, 20, 25 and 30 minutes after injection)
- Duration of motor block(from time of injection to 2, 4, 6, 8, 10 and 12 hours post operatively or upto motor block receeding.)
- time to first analgesic requirement(to be assessed at 2,4,6,8,10 & 12 hours post operatively for pain)
- Incidence of block failure(assessed at 0, 5, 10, 15, 20, 25 up to 30 mins after injection)
研究者
Dr Diksha Dmello
Manipal Academy of Higher Education