Biokinetic of the rare sugar D-Allulose in human blood and urine
Not Applicable
Recruiting
- Conditions
- Allulose biokinetic in blood and urine
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
Healthy women and men
- BMI 18.5 - 30 kg/m2
- informed written consent
- good metabolic health
- no dietary sensitivities e.g fructose malabsorption, IBD...
- normal range parameters for liver and kidney function, blood lipids, inflammation markers (screening blood sample)
- non-smokers
- no chronic intake of medication (except hormonal contraceptives)
- no intake of antibiotics in the prior 6 months
- no pregnancy or lactation phase
- no known allergies against components of the study foods
Exclusion Criteria
see inclusion criteria
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Allulose concentration (mg/dl) in plasma at t=2h after allulose consumption<br>Excreted amount of allulose (g) in urine in the 12h after allulose consumption
- Secondary Outcome Measures
Name Time Method Anthropometric data<br>Plasma - glucose, lactate, insulin<br>Blood lipids, fasting and late postprandal (LDL-C; HDL-C; TG; apoB, apoCIII, apoA1)<br>microbiome composition in urine<br>Allulose in saliva at baseline and 1h and 4h after allulose consumption<br>Allulose Cmax, tmax and AUC in plasma and urine