ACTRN12616001652460已完成未知
To determine if critical illness impairs protein absorption compared to health
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •ICU patients:
- •*Adults (greater than or equal to 18 years of age)
- •*Admitted to the Royal Adelaide Hospital Intensive Care Unit
- •*Mechanically ventilated
- •*Suitable for enteral feeding
- •*Arterial line insitu
- •*Consent obtained
- •Healthy volunteer arm:
- •*Adults (greater than or equal to 18 years of age)
排除标准
- •ICU patients:
- •*Recent upper abdominal surgery
- •*Lactose intolerance
- •*Any order to withhold active treatment
- •*Jehovah’s Witness
- •*For muscle biopsy: Bleeding diathesis (INR > 1.5; APTT > 50) including those receiving anticoagulants (other than low dose for DVT prophylaxis) and anti-platelet agents
- •Healthy volunteer arm:
- •*Significant illness
- •*Smokers (cigarettes/cigars/marijuana)
- •*Intake of >2 standard drinks on >5 days per week
- •*Intake of >4 cups of caffeinated drinks per day
- •*Intake of any illicit substance
- •*Lactose intolerance
- •*Use of prescribed or non-prescribed medications that may affect gastrointestinal function
- •*Significant gastrointestinal symptoms, disease or surgery (apart from uncomplicated appendectomy)
- •*For muscle biopsy: Bleeding diathesis (INR > 1.5; APTT > 50) including those receiving anticoagulants (other than low dose for DVT prophylaxis) and anti-platelet agents
研究者
相似试验
撤回
不适用
Protein and energy interactions in critically ill childreDiabetes type 21001842410037008Insulin resistanceNL-OMON32972Erasmus MC, Universitair Medisch Centrum Rotterdam46
撤回
不适用
Optimal Protein Supplementation for Critically Ill PatientsCritical IllnessNCT01934595University of Oklahoma
撤回
3 期
The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Randomized TrialNutritional DisorderCritical IllnessMalnutritionFrailtySarcopeniaNCT04012333RWTH Aachen University
进行中（未招募）
1 期
The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Randomized Trialutritionally high-risk critically ill mechanically ventilated patients. In this sub-study, eligible and enrolled patients randomized to the high protein dose group will achieve its protein goals by adding high protein PN to EN (combined EN/PN). For patients enrolled to the low dose group, goals can be achieved by EN only.EUCTR2018-003703-19-DERWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty142
尚未招募
不适用
Insulin and protein in critically ill children.Critically Ill septic Children admitted to the PICNL-OMON29492ErasmusMC - Sophia Children's Hospital30