se of Vaginal Misoprostol to Relieve Pain During Operative Hysteroscopy in Office Setting: A Randomized Double-Blinded Placebo Controlled Study

Phase 2

Recruiting

• Conditions: Reproductive age women who had intrauterine lesion that require Operative Hysteroscopy in office setting; Misoprostol, Operative Hysteroscopy, office setting, visual analog scale

• Registration Number: TCTR20230621006
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-21
• Study Completion: 2024-04-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 78

Inclusion Criteria

1 Women who had an appointment for operative hysteroscopy in outpatient department at ramathibodi hospital
2 age 18-50 years and in reproductive age
3 pelvic examination can done
4 BMI 18-30 kg/m2
5 Have confirm test from ultrasound or diagnostic hysteroscopy that have intrauterine lesion that require surgery such as endometrial polyp, myoma uteri size less than 3 cm., intrauterine adhesion, uterine septum, foreign body
6 Be willing to participate in the research and sign a consent letter

Exclusion Criteria

1 Have contraindication for hysteroscopy such as pregnancy, pelvic inflammatory disease, suscepted cervical cancer or advance stage endometrial cancer
2 Underlying disease such as asthma, chronic kidney disease or hepatitis
3 Allergy to Misoprostol, NSIADs
4 Cervical stenosis or history cervical operation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Compared efficacy of the use of misoprostol to relieve pain during operative hysteroscopy in office setting compared with placebo During office hysteroscopy Visual analog scale