A study to compare two different drugs for acute blood pressure control during pregnancy

Not Applicable

• Conditions: Health Condition 1: null- pregnant women with hypertensive emergencies (BP more than 160 and or 110 mm of Hg at more than 24 weeks pregnancy)

• Registration Number: CTRI/2014/12/005285
• Lead Sponsor: Government of Himachal Pradesh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

1.Age between 18 to 45 years,

2.Period of gestation > 24 weeks of gestation

3.Maternal Heart rate; 60-90 beats per minute

4.Reassuring fetal heart rate.

Exclusion Criteria

1.known case of heart disease (pre-existing angina)

2.Non-pregnancy related hypertension (diagnosed cases of chronic or secondary hypertension)

3.Allergy to either of the drug

4.Need for any acute emergency for cesarean section (Abruptio placentae, severe fetal bradycardia etc)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time required to achieve target systolic BP of 150 mm of Hg or lower and diastolic BP of 100 mm of Hg or lower (both targets had to be fulfilled).Timepoint: 2 hours after delivery

Secondary Outcome Measures

Name	Time	Method
ï??Total number of antihypertensive dosages required to achieve the target BP (systolic BP of 150 mm of Hg or lower and diastolic BP of 100 mm of Hg or lower, both to be fulfilled) <br/ ><br>ï??Maternal heart rate profile during the study period <br/ ><br>ï??Maternal hypotension (BP less than 90/60 mm Hg) <br/ ><br>ï??Side effects profile (Nausea, Vomiting, Headache, dizziness, urticaria, flushing, pruritis, nasal congestion, conjunctivitis, palpitations) <br/ ><br>ï??Perinatal outcome <br/ ><br>Timepoint: 2 hours after delivery