A study to compare two different drugs for acute blood pressure control during pregnancy
Not Applicable
- Conditions
- Health Condition 1: null- pregnant women with hypertensive emergencies (BP more than 160 and or 110 mm of Hg at more than 24 weeks pregnancy)
- Registration Number
- CTRI/2014/12/005285
- Lead Sponsor
- Government of Himachal Pradesh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1.Age between 18 to 45 years,
2.Period of gestation > 24 weeks of gestation
3.Maternal Heart rate; 60-90 beats per minute
4.Reassuring fetal heart rate.
Exclusion Criteria
1.known case of heart disease (pre-existing angina)
2.Non-pregnancy related hypertension (diagnosed cases of chronic or secondary hypertension)
3.Allergy to either of the drug
4.Need for any acute emergency for cesarean section (Abruptio placentae, severe fetal bradycardia etc)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time required to achieve target systolic BP of 150 mm of Hg or lower and diastolic BP of 100 mm of Hg or lower (both targets had to be fulfilled).Timepoint: 2 hours after delivery
- Secondary Outcome Measures
Name Time Method ï??Total number of antihypertensive dosages required to achieve the target BP (systolic BP of 150 mm of Hg or lower and diastolic BP of 100 mm of Hg or lower, both to be fulfilled) <br/ ><br>ï??Maternal heart rate profile during the study period <br/ ><br>ï??Maternal hypotension (BP less than 90/60 mm Hg) <br/ ><br>ï??Side effects profile (Nausea, Vomiting, Headache, dizziness, urticaria, flushing, pruritis, nasal congestion, conjunctivitis, palpitations) <br/ ><br>ï??Perinatal outcome <br/ ><br>Timepoint: 2 hours after delivery