Efficacy of hypertonic saline in acute bronchiolitis
Phase 2
- Conditions
- Acute bronchiolitis.with bronchospasm
- Registration Number
- IRCT20141201020175N3
- Lead Sponsor
- Vice-chancellor of research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
acute onset of respiratory distress
prodromal respiratory symptoms
presence of wheezing on examination
severity score (BRAS) equal five or more
infants 1-24 months old
Exclusion Criteria
history of atopy
history of prematurity (birth before 34 weeks or equal to)
history of wheezing
history of previous use of bronchodilators or glucocorticoids use
loss of consciousness
history of chronic heart, pulmonary, neurologic, oncologic and immunologic disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bronchiolitis respiratory assessment score (BRAS). Timepoint: Before intervention and then every 4 hours. Method of measurement: Bronchiolitis respiratory assessment score (BRAS).;Length of hospital stay. Timepoint: At discharge. Method of measurement: Patient record.
- Secondary Outcome Measures
Name Time Method Respiratory rate. Timepoint: Before intervention and then every 4 hour. Method of measurement: observation.;Temperature. Timepoint: Before intervention and then every 4 hour. Method of measurement: Thermometer.;Heart rate. Timepoint: Before intervention and then every 4 hour. Method of measurement: determining pulse rate by use a chronometer.;O2 saturation. Timepoint: Before intervention and then every 4 hour. Method of measurement: pulse oximeter.