Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/NCT01523717
NCT01523717CompletedNot Applicable

Procalcitonin Decrease Over 72 Hours and Outcome in Patients With Severe Sepsis or Septic Shock

Brahms AG13 sites in 1 country858 target enrollmentStarted: December 2011Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
858
Locations
13
Primary Endpoint
28 day all cause mortality
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The purpose of this study is to investigate the relationship between a procalcitonin decrease over 72 hours and outcome in patients who have severe sepsis or septic shock.

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Adult patients (i.e. >18 years of age) diagnosed with severe sepsis or septic shock as defined in Appendix 1, who are already in the ICU or come from the ED, other wards or directly from out of hospital
  • •Blood sample collection within 12 hours after diagnosis "severe sepsis or septic shock"No prior enrollment into this study
  • •Written informed consent

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

28 day all cause mortality

Time Frame: within 28 day safter inlclusion

participants will be followed up for 28 days

Secondary Outcomes

  • all-cause in-hospital mortality(mortality during hospital stay)

Investigators

Sponsor
Brahms AG
Sponsor Class
Industry
Responsible Party
Sponsor

Study Sites (13)

Loading locations...

Similar Trials

Completed
Not Applicable
Procalcitonin Use in Pneumonia Patients in the Critical Care SettingPneumonia
NCT01788488Mayo Clinic134
Completed
Not Applicable
Procalcitonin guided reduction of the duration of antibiotic therapy in Community Acquired PneumoniaCommunity Acquired Pneumonia (CAP)RespiratoryPneumonia
ISRCTN04176397niversity Hospital Basel (Switzerland)250
Completed
Not Applicable
Effect of Procalcitonin Guidance for Duration of Antibiotic Therapy on Antibiotics Use in Aspiration Pneumonia Randomized Controlled Trialaspiration pneumonia
JPRN-UMIN000004800Hamamatsu Medical Center100
Completed
Not Applicable
Procalcitonin at Zero and 24 Hours as a Prognostic Factor in Patients With PneumoniaPneumonia
NCT03711227Spectrum Health - Lakeland185
Unknown
Phase 3
PROcalcitonin to SHORTen Antibiotics Duration in PEDiatricICU Patients (ProShort-Ped) TrialSepsis
NCT01652404Hunan Children's Hospital600