Procalcitonin guided reduction of the duration of antibiotic therapy in Community Acquired Pneumonia

niversity Hospital Basel (Switzerland)0 个研究点目标入组 250 人开始时间: 2005年2月15日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•The criterion for inclusion in the study was a suspected CAP as the main diagnosis. This was defined as presence of a new infiltrate on chest X-ray accompanied by one or several acquired respiratory symptoms and signs:
•2. Sputum production
•3. Dyspnoea
•4. Fever over 38.0°C
•5. Auscultatory findings of abnormal breath sounds and rales
•6. Leukocytosis more than 10 x 10^9 cells/L or leukopenia less than 4 x 10^9 cells/L in the absence of a hospital stay within 14 days before admission

•1. Cystic fibrosis or active tuberculosis
•2. Immunocompromised patients, i.e. patients infected with Human Immunodeficiency Virus (HIV) infection and a CD4 count below 200
•3. Neutropenic patients with a neutrophil count less than 500 x 10^9/ml
•4. Under chemotherapy with neutrophils 500 - 1000 x 10^9/ml with an expected decrease to values less than 500 x 10^9/ml
•5. Immunosuppressive therapy after bone marrow or solid organ transplantation
•6. Nosocomial pneumonia

发起方

niversity Hospital Basel (Switzerland)