ISRCTN04176397
已完成
不适用
Procalcitonin guided reduction of the duration of antibiotic therapy in Community Acquired Pneumonia
niversity Hospital Basel (Switzerland)0 个研究点目标入组 250 人2005年2月15日
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Community Acquired Pneumonia (CAP)
- 发起方
- niversity Hospital Basel (Switzerland)
- 入组人数
- 250
- 状态
- 已完成
- 最后更新
- 11年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •The criterion for inclusion in the study was a suspected CAP as the main diagnosis. This was defined as presence of a new infiltrate on chest X\-ray accompanied by one or several acquired respiratory symptoms and signs:
- •2\. Sputum production
- •3\. Dyspnoea
- •4\. Fever over 38\.0°C
- •5\. Auscultatory findings of abnormal breath sounds and rales
- •6\. Leukocytosis more than 10 x 10^9 cells/L or leukopenia less than 4 x 10^9 cells/L in the absence of a hospital stay within 14 days before admission
排除标准
- •1\. Cystic fibrosis or active tuberculosis
- •2\. Immunocompromised patients, i.e. patients infected with Human Immunodeficiency Virus (HIV) infection and a CD4 count below 200
- •3\. Neutropenic patients with a neutrophil count less than 500 x 10^9/ml
- •4\. Under chemotherapy with neutrophils 500 \- 1000 x 10^9/ml with an expected decrease to values less than 500 x 10^9/ml
- •5\. Immunosuppressive therapy after bone marrow or solid organ transplantation
- •6\. Nosocomial pneumonia
结局指标
主要结局
未指定
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