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Pain control in bone marrow aspiration and biopsy

Phase 2
Recruiting
Conditions
Bone marrow disease.
Multiple myeloma and malignant plasma cell neoplasms
Registration Number
IRCT20200427047215N2
Lead Sponsor
Esfahan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
44
Inclusion Criteria

Age 18-55 years
Conscious consent to enter the study
BMI 18-25

Exclusion Criteria

Mental retardation
Generalized anxiety disorder
Major Depressive Disorder
Pregnancy
Lactation
Drug addiction
Take analgesic less than 4 hours before admission
Hypersensitivity to apotel, promethazine and lidocaine
GFR < 30
Cirrhosis Child B & C

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Reduction of pain during bone marrow biopsy and aspiration. Timepoint: Immediately after completing the procedure and 30 minutes later in the intervention and control groups. Method of measurement: To estimate the severity of pain and the effect of the drug in relieving the patient's pain from the quantitative scale VAS(Visual Analog Scale) is used.;Anxiety after completing the procedure. Timepoint: After the procedure and 30 minutes later, the patient's anxiety is rated from 1 to 10, depending on the severity. Method of measurement: Anxiety severity is divided from zero to ten using a questionnaire.
Secondary Outcome Measures
NameTimeMethod
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