Effect of Laser Acupuncture Alone or Combined With Pranayama Exercise on Inflammation in Allergic Rhinitis

Not Applicable

Recruiting

• Conditions: Allergic Rhinitis
• Interventions: Other: pranayama plus acupoint stimulation by laser; Other: acupoint stimulation by laser

• Registration Number: NCT05553483
• Lead Sponsor: Cairo University

Brief Summary

Allergic rhinitis (AR) represents one of the most common global health problems with seriously increasing incidence over the last decades.The goal of the treatment of rhinitis is to prevent or reduce the symptoms through reduction of the inflammation of affected tissues. Acupuncture and pranayama yoga exercises had reported a significant improvement in daily symptoms and an increase of symptom-free days in many studies enrolling patients.

Detailed Description

Sixty Egyptian children with allergic rhinitis, after randomization, will be divided to 2 groups; the first 30-children group will receive 2-session per-week laser stimulation for 6 weeks to some selected acupoints and daily pranyama exercises (nearly every session will be one hour, for six weeks), the second group will receive 2-session per-week laser stimulation for six weeks to some bilateral selected acupoints. the stimulated points will be (LI 19, LI 20, ST2, and ST4. ST6, ST7, ST17, ST36, SI18, BL2, GB14, GV24 and EXHN5). Every acupoint will be stimulated with laser power of 100 mw that will be used on a spot area of 1 cm2 for 1 minute.

Study Timeline

• Study Start: 2021-09-15
• Status Verified: 2022-09
• Study First Submitted: 2022-09-21
• Study First Submitted QC: 2022-09-21
• Last Update Submitted: 2022-09-21
• Study First Posted: 2022-09-23
• Last Update Posted: 2022-09-23
• Primary Completion: 2022-12-01
• Study Completion: 2022-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• allergic rhinitis children
• physician-based diagnosis of allergic rhinitis

Exclusion Criteria

• children with intellectual disabilities
• chest disease or heart disease or local congenital nose deformities
• participants received within-previous-six-months self-prescribed or by-therapist prescribed complementary therapies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
pranayama and acupoint stimulation by laser	pranayama plus acupoint stimulation by laser	for 6 weeks,This 30-children group will receive 2-session per-week laser stimulation to some selected acupoints and daily pranyama exercises (nearly every session will be one hour), the stimulated bilateral acupoints will be (LI 19, LI 20, ST2, and ST4. ST6, ST7, ST17, ST36, SI18, BL2, GB14, GV24 and EXHN5). Every acupoint will be stimulated with laser power of 100 mw that will be used on a spot area of 1 cm2 for 1 minute. this group will receive also pranayama session (applied daily, one hour approximately, for six weeks) will be (alternate nostril pranayama, diaphragmatic pranayama, rapid abdominal pranayama, Bhramari pranayama)
acupoint stimulation by laser	acupoint stimulation by laser	for six weeks, This 30-children group will receive 2-session per-week laser stimulation to some selected acupoints. The stimulated bilateral points will be (LI 19, LI 20, ST2, and ST4. ST6, ST7, ST17, ST36, SI18, BL2, GB14, GV24 and EXHN5). Every acupoint will be stimulated with laser power of 100 mw that will be used on a spot area of 1 cm2 for 1 minute.

Primary Outcome Measures

Name	Time	Method
erothrocyte sidemention rate	It will be measured after 6 weeks	it is a inflammatory marker in serum

Secondary Outcome Measures

Name	Time	Method
Immunoglobulin E	It will be measured after 6 weeks	it is an antibody in the serum
C-reactive protein	It will be measured after 6 weeks	it is a inflammatory marker in serum
total eosinophil count	It will be measured after 6 weeks	it is a inflammatory marker in serum
interleukin 1-beta	It will be measured after 6 weeks	it is a inflammatory marker in serum

Trial Locations

Locations (1)

Cairo Unoversity; 🇪🇬 Giza, Egypt