MedPath

rine Biomarkers in Cirrhotic Patients with Acute Kidney Injury

Not Applicable
Recruiting
Conditions
Acute kidney injury
Cirrhosis
Novel biomarker
Registration Number
TCTR20180905002
Lead Sponsor
Rachadapisek Sompot Fund
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
107
Inclusion Criteria

1. Hospitalized cirrhotic patients with risk of acute kidney injury

Exclusion Criteria

1. Chronic kidney disease or need renal replacement therapy
3. Post renal acute kidney injury or acute glomerulonephritis or acute interstitial nephritis
4. Liver or kidney transplant
5. Need for immunosuppressive drug other than for treatment of severe alcoholic hepatitis
6. Pregnancy

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Diagnosis of acute kidney injury by urine LFABP and NGAL compared with serum creatinine Up to 7 days of admission Level of urine LFABP and urine NGAL on the day of acute kidney injury diagnosed by serum creatinine
Secondary Outcome Measures
NameTimeMethod
Diagnosis of hepatorenal syndrome and acute tubular necrosis by urine LFABP and NGAL Up to 7 days of admission Level of urine LFABP and urine NGAL on the day of hepatorenal syndrome and acute tubular necrosis di
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