Intestinal Fatty Acid Binding Protein as a Marker for Increased Intra-Abdominal Pressure (I-Fabulous study)
- Conditions
- Intra-abdominal hypertension and abdominal compartment syndrome
- Registration Number
- NL-OMON29639
- Lead Sponsor
- Erasmus MC, University Medical Center Rotterdam, Trauma Research Unit, Department of Surgery
- Brief Summary
Strang SG, Van Waes OJF, Van der Hoven B, Ali S, Verhofstad MHJ, Pickkers P, Van Lieshout EMM. Intestinal fatty acid binding protein as a marker for intra-abdominal pressure-related complications in patients admitted to the intensive care unit; study protocol for a prospective cohort study (I-Fabulous study). Scand J Trauma Resusc Emerg Med. 2015 Jan 16;23(1):6.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
1. Patients with at least two risk factors as agreed by the World Society of the Abdominal Compartment Syndrome (WSACS)
2. Age 18 or older, with no upper age limit
1. Patients with bladder trauma or hematuria in whom intra-bladder pressure measurement is contra-indicated
2. Patients in whom intra-bladder pressure measurements are not possible due to intraperitoneal adhesions, bladder oppressive pelvic hematoma, abdominal packs in situ, or previous bladder removal
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intestinal Fatty Acid Binding Protein (I-FABP) level in urine
- Secondary Outcome Measures
Name Time Method Claudin-3 level in urine and serum<br /><br>I-FABP level in serum