Intestinal Fatty Acid Binding Protein in Very Low Birth Weight Infants With Meconium Obstruction

Completed

• Conditions: Meconium Obstruction of Prematurity

• Registration Number: NCT02864446
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Urinary intestinal fatty acid binding protein (i-FABP), a marker of intestinal mucosal cell damage, has recently been proposed as a clinically useful measure in the early detection of necrotizing enterocolitis (NEC). However, there are no data on urinary i-FABP in meconium obstruction of prematurity (MOP). This study aimed to evaluate urinary i-FABP in MOP patient as a marker for early detection.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-10
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Status Verified: 2016-08
• Study First Submitted: 2016-08-02
• Study First Submitted QC: 2016-08-10
• Last Update Submitted: 2016-08-10
• Study First Posted: 2016-08-12
• Last Update Posted: 2016-08-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• preterm infants weighing <1,250g

Exclusion Criteria

• major congenital anomalies
• perinatal asphyxia (cord pH <7.0)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of i-FABP level between the meconium obstruction group and the normal feeding advance group	within 48 hours after birth

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of