Evaluation of the effect of erythropoetin mouthwash in mucositis

Phase 3

• Conditions: Condition 1: multiple myeloma. Condition 2: Non-Hodgkin lymphoma. Condition 3: Hodgkin lymphoma.; Non-Hodgkin lymphoma, unspecified; multiple myeloma; Hodgkin lymphoma, unspecified

• Registration Number: IRCT2015042518842N8
• Lead Sponsor: Hematology, Oncology and Stem Cell Transplantation Research Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

inclusion criteria: age of at least 18 years old; patients with NHL, HD or MM receiving conditioning chemotherapy before autologousHSCT; signing written informed consent. exclusion criteria: Karnofsky performance status <70% or participation in another study; using an unlicensed product.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence, severity and duration of oral mucositis. Timepoint: The starting day of preparing chemotherapy until day +21 after transplantation. Method of measurement: Daily oral examination based on the WHO criteria for grading mucositis.

Secondary Outcome Measures

Name	Time	Method
eutrophil and platelet engraftment. Timepoint: The starting day of preparing chemotherapy until day +21 after transplantation. Method of measurement: CBC test.;Duration of neutropenia. Timepoint: The starting day of preparing chemotherapy until day +21 after transplantation. Method of measurement: CBC test.;Duration of fever due to neutropenia. Timepoint: The starting day of preparing chemotherapy until day +21 after transplantation. Method of measurement: Temperatures measured under the tongue.;Duration of hospitalization. Timepoint: Discharge Time. Method of measurement: The number of hospitalization days.