Evaluation of the effect of topical erythropoietin on healing of chemical burn grade 3 and 4 clinical trial study

Not Applicable

Recruiting

• Conditions: Treatment of chemical burns of the eye surface.; Unspecified injury of eye and orbit; S05.9

• Registration Number: IRCT20230510058143N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

Patients who have suffered grade 3 and 4 corneal damage (according to the Roper-Hall classification) due to chemical burns and have presented to thelabbafinezhad hospital in the acute stage

Exclusion Criteria

History of diabetic retinopathy
Neovascular glaucoma
Eye surface tumors

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Avascular lesions. Timepoint: First day of examination, first week, first month, third and fourth. Method of measurement: by PhotoSlit and and with the help of Image J software by an operator.;Epithelial defect. Timepoint: First day of examination, first week, first month, third and fourth. Method of measurement: Fluorescein staining by the ophthalmologist.;Corneal transparency. Timepoint: First day of examination, first week, first month, third and fourth. Method of measurement: Roper-Hall classification.

Secondary Outcome Measures

Name	Time	Method
Best corrected visual acuity (BCVA). Timepoint: First day of examination, first week, first month, third and fourth. Method of measurement: Tumbling E-chart.