Investigation of the Effect of cervical Mobilization on Migraine by functional Magnetic Resonance Imaging (fMRI) findings

Not Applicable

Conditions: Migraine.
Migraine without aura
G43.0

Registration Number: IRCT20170524034119N3

Lead Sponsor: Tarbiat Modares University

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 30

Inclusion Criteria

Diagnosis of episodic migraine without aura by a neurologist
The minimum duration of the disease is one year
Number of attacks at least 2-5 attacks per month
No change in medications in the last three months

Exclusion Criteria

Positive response to VBI tests of Alar ligament, Transverse ligament, Tectorial membrane
Any abnormal signs in the structural condition of the cervical spines in X-Ray findings
Symptoms of Vertebrobasilar Insufficiency (VBI)
Malignancy, Diabetes, Rheumatoid disease, peripheral neuropathy, Fibromyalgia, Osteoporosis, history of surgery, radiculopathy, disc dysfunction or soft tissue elements in the neck
Performing Nerve Block or non-drug treatment (Physiotherapy, Manual therapy, Acupuncture, etc.) in the last 6 months

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brain fMRI findings. Timepoint: before the intervention, 5 weeks after the start of the intervention (after the intervention). Method of measurement: fMRI image analysis.;Midas Disability Questionnaire Score (MIDAS). Timepoint: Before the intervention and 12 weeks after the last intervention session. Method of measurement: The MIDAS (Migraine Disability Assessment) questionnaire.;Mean severity of attacks in people with migraine (VAS). Timepoint: Before the intervention, after ten session intervention and 12 weeks after the last intervention session. Method of measurement: The visual analog scale (VAS).;Questionnaire score of the impact of headache on the life of people with migraine (HIT-6). Timepoint: Before the intervention, after ten session intervention and 12 weeks after the last intervention session. Method of measurement: Headache Impact Test-6 (HIT-6) for Migraine Patients questionnaire.

Secondary Outcome Measures