Does infiltration of local anaesthesia improve recovery after anterior hip replacement?

Phase 4

Completed

• Conditions: total hip replacement; local infiltration analgesia; postoperative recovery; Anaesthesiology - Pain management; Musculoskeletal - Osteoarthritis; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12615000844549
• Lead Sponsor: Dr Nicole Tan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-08-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

Patients aged 50 - 80 years undergoing primary unilateral anterior THR for osteoarthritis, who are able to provide informed consent.

Exclusion Criteria

Patients will not be eligible if they take regular opioids other than codeine, have an allergy or contraindication to the proposed analgesic or anaesthetic technique, ASA > 3, BMI > 40, are pregnant, have undergone lower limb joint replacement in the preceding 6 months or are scheduled for any further surgery within 30 days.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of Recovery-15 score. QoR-15 is a well-validated patient reported outcome measure, designed to assess generic early postoperative quality of recovery. It consists of 15 questions on an 11 point scale to give a potential total score of 150. The questions are whether the participant has ‘been able to breathe easily’, ‘been able to enjoy food’, ‘feeling rested’, ‘have had a good sleep’, ‘able to look after personal toilet and hygiene unaided’, ‘able to communicate with family or friends’, ‘getting support from hospital doctors and nurses’, ‘able to return to work or usual home activities’, ‘feeling comfortable and in control’, ‘having a feeling of general well-being’, ‘moderate pain’, ‘severe pain’, ‘nausea or vomiting’, ‘feeling worried or anxious’ and ‘feeling sad or depressed’. [Postoperative day 1]

Secondary Outcome Measures

Name	Time	Method
umerical Rating Score for pain - worst NRS at rest and on movement in the past 24 hours[Postoperative day 1 and 2];Oral morphine equivalent consumption - total dose of oral oxycodone and converted dose of intravenous fentanyl recorded on the patient drug chart in the past 24 hours[Postoperative day 1 and 2];10-metre Walk Test (10MWT) - time taken for the patient to walk 10 metres, as measured by the treating physiotherapist[Postoperative day 1];Length of hospital stay - defined by readiness for discharge, in days, from hospital records. [Day of discharge from hospital acute ward];Brief Pain Inventory. The Brief Pain Inventory (BPI) is a self-report measure which assesses pain and its interference with physical and emotional functioning and has established reliability and validity. Its use is supported by the IMMPACT recommendations for assessing pain in clinical trials [Postoperative day 90]