Immuno-humoral Rejection Markers in Pulmonary Transplant
Not Applicable
Completed
- Conditions
- Lung Transplant
- Interventions
- Biological: Blood test for detecting the circulatory anti-HLA antibodies by ELISA and LUMINEX tests
- Registration Number
- NCT01791166
- Lead Sponsor
- Hopital Foch
- Brief Summary
Open multicentric prospective study performed on pulmonary transplanted patients to detect the values of different diagnostic markers for immuno- humoral reaction and their roles in the humoral rejection for those patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 53
Inclusion Criteria
- Both genders, more than 18 years of age.
- Patients with or without Cystic fibrosis
- Patients with no previous unilateral or bilateral pulmonary transplant or cardiopulmonary transplant
- Patients with no current other disease can affect, in short term, the process or prognosis of the transplant
- Patients had given his agreement to be enrolled in the study
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Exclusion Criteria
- Patient less than 18 year-old
- Patient had previous organ transplant
- Pregnant and/or lactating women
- Female subject in reproductive age does not use effective contraceptive methode
- Alcoholisms or neuropsychosis, conditions that affect the good comprehension of the study
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Pulmonary transplant Blood test for detecting the circulatory anti-HLA antibodies by ELISA and LUMINEX tests -
- Primary Outcome Measures
Name Time Method Incidence of immune Markers of acute lung transplant rejection (Anti-HLA circulatory antibodies, neutrophils and C4d immune markers. 12 months after pulmonary transplant
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hôpital FOCH
🇫🇷Suresnes, Ile de France, France