Prediction of ST2 for impRovement of Left ventricUlar Systolic funcTion After Percutaneous Coronary Intervention in Patients With acutE Coronary synDrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- ST2 and LV end-diastolic volume index
研究概览
简要总结
Patients who underwent percutaneous coronary intervention after diagnosis of acute coronary syndrome should be enrolled in the study and follow - up.
详细描述
Obtain written consent for patients who meet all of the selection criteria and who do not meet the exclusion criteria.
ACS(Acute Coronary Syndrome) patients with LV systolic dysfunction(LVEF<50%) on TTE test who underwent successful PCI. At that time, patient proceed with the Baseline blood test(ST2) in hospital.
And then, Medical therapy for 3 months later patient proceed with the Follow-up blood test(ST2) and TTE in OPD.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects aged 19 or older
- •Patients with acute coronary syndrome who underwent successful percutaneous coronary intervention
- •Patients with left ventricular ejection fraction less than 50% on transthoracic echocardiography
- •Patients who voluntarily agreed to participate in the study
排除标准
- •Failure to obtain TIMI 3 flow after procedure
- •If the remaining life span is less than one year
- •Women who are breastfeeding or plan to become pregnant or are planning to become pregnant during the study period
结局指标
主要结局
ST2 and LV end-diastolic volume index
时间窗: 3 months
the correlation between changes of ST2 and LV end-diastolic volume index
次要结局
- ST2 and LV ejection fraction(3 months)
- ST2 and E over e' ratio(3 months)
- ST2 and LV wall motion score(3 months)
研究者
Kim Hyungseop
Professor
Keimyung University Dongsan Medical Center