The Effect of Dexmedetomidine as an Adjuvant to Desflurane Anesthesia on Hepatocellular Functions in Patients with Chronic Liver Disease Undergoing Lower Abdominal Surgery
Phase 3
Completed
- Conditions
- Anaesthesia
- Registration Number
- PACTR202402578309242
- Lead Sponsor
- Theodor Bilharz Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 82
Inclusion Criteria
Male and female
Aged 30-60 years
BMI between 18 and 35 Kg/m2
Child-Pugh-Turcotte class A
ASA physical status classes II or III
Scheduled for elective lower abdominal surgery
Exclusion Criteria
Spontaneous bacterial peritonitis
Complicated cholecystitis
Disseminated malignant tumor
Cardiovascular disease
Renal failure requiring dialysis
Child-Pugh-Turcotte class B or more
INR > 1.5
Platelets count = 50,000/mm3
Tense or refractory ascites
Serum sodium = 120 mEq/l
Allergy for the study’s medications
Neurological or mental disease
Bronchial asthma
Hematological disorder (not caused by chronic liver disease)
Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method