a clinical trial to study the efficacy of combination of two drugs,ampicillin plus azithromycin and ampicillin plus erythromycin in pregnant patients with preterm premature rupture of membranes
- Conditions
- Health Condition 1: null- pregnant with preterm premature rupture of membranes
- Registration Number
- CTRI/2018/03/012449
- Lead Sponsor
- RGKAR MEDICAL COLLEGE KOLKATA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 114
Pregnant women of 19 years to 40 years of age with preterm premature rupture of membranes and not in labour.
Gestational age of 28 to 34 weeks.
Single foetus gestation
Randomization within 36 hours of rupture of membranes.
Cervical dilatation less than or equal 04 cm.
Gestational age <24 weeks and >34 weeks
In preterm labour
Cervical cerclage in situ
Multifetal gestation
Vaginal bleeding/Foul smelling vaginal discharge
Maternal or foetal indication for delivery
Placental abnormality
H/o amniocentesis
Had received corticosteroid or antibiotic within the last seven days
Carrying a foetus with lethal anomalies
H/o foetal surgery
H/o abdominal trauma
On antiretroviral therapy
Known allergy or cntraindication to use of ampicillin, azithromycin and erythromycin.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method