The effect of plant stanol ester consumption on the vaccination response to a COVID-19 vaccine
Completed
- Conditions
- obesityOverweight10013317
- Registration Number
- NL-OMON51220
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Men and women, 18 years or older, BMI 27-35 kg/m2, not using products with
added plant sterols or plant stanols, willing to abstain from products with
added plant sterols or plant stanols during study, willing to keep intake of
fish oil and vitamin supplements constant during study
Exclusion Criteria
Already received COVID-19 vaccination, already had a positive test for COVID-19
(all tests, e.g. PCR test or antibody test), allergy to an ingredient of the
mini drinks, excessive alcohol use (>20 consumptions per week), regular use of
drugs, blood donors that want to donate one month prior to or during the study,
pregnant or breastfeeding women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study endpoint is vaccination response to a COVID-19 vaccine. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary endpoints include amongst others hematological, inflammatory and<br /><br>immunological parameters (e.g. hs-CRP, leukocyte differential count) and<br /><br>metabolic markers (e.g. blood lipid profiles, plasma glucose, serum insulin,<br /><br>HOMA-IR).</p><br>