JPRN-jRCT1031190027已完成未知
A multicenter single-blind randomized study to compare effects of continuing and withholding angiotensin receptor blocker(ARB)-calcium blocker (CAB) combination tablets before surgery on perioperative hemodynamics in patients undergoing non-cardiac surgery - Effects of continuing vs withholding ARB/CAB combination tablets before surgery on perioperative hemodynamics
Hayashida Masakazu0 个研究点目标入组 110 人开始时间: 2019年5月22日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 110
研究概览
简要总结
Continuation of ARB/CCB combination tablets was effective in preventing hypertension before anesthesia. However, it increased a risk of hypotension during anesthesia and increased requirements of vasoconstrictor therapy. Further, it was not effective in preventing postoperative hypertension. Therefore, discontinuation of ARB/CCB combination tablets prior to general anesthesia seemed preferable to their continuation.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 80age old（—）
- 性别
- All
入选标准
- •Surgical patients with hypertension treated with ARB/CAB combination tablets
排除标准
- •Patients having severe comorbidities, including heart disease, and those scheduled for major surgery including cardiac surgery
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