Evaluation of a novel genetic testing system for detection of macrolide resistance Mycoplasma pneumoniae
Not Applicable
- Conditions
- Mycoplasma pneumoniae infection
- Registration Number
- JPRN-UMIN000036804
- Lead Sponsor
- Saga University
- Brief Summary
A clinical evaluation of SmartGene TM Myco was conducted in 150 children suspected of being infected with M. pneumoniae. The sensitivity when using real-time PCR as a control was 97.8%, the specificity was 93.3%, and the concordance rate for macrolide resistance mutation determination when using sequence analysis as a control was 100%. Post-test antibiotic change rates were significantly higher in patients with mutations.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients who could not collect enough samples for evaluation. (2) Patients who the research director judged inappropriate as a research subject.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detection performance of Mycoplasma pneumoniae gene
- Secondary Outcome Measures
Name Time Method