NCT05535751已完成不适用
Cefepime vs. Carbapenems for Treating AmpC β-lactamase-producing Enterobacteriaceae Bloodstream Infections
University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2022年7月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Hospital mortality
研究概览
简要总结
Recent international recommendations suggest the use of carbapenem rather than cefepime in this situation, but with a low level of evidence, given the few existing studies. As cefepime is a less broad-spectrum antibiotic than carbapenems, its use would limit the selection of multidrug-resistant bacteria.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Patient who has expressed opposition to the reuse of their data for scientific research purposes.
- •Resistance to Cefepime or carbapenems
- •Multiple bacteremia
- •Treatment with a molecule other than Cefepime or carbapenem.
结局指标
主要结局
Hospital mortality
时间窗: 30 days after infection
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Carbapenem Antibiotic Therapy for VIM Carbapenemase-Producing Enterobacteriaceae InfectionsCarbapenemase-Producing EnterobacteriaceaeNCT06185153University Hospital, Strasbourg, France70
Unknown
3 期
Prolonged Infusion Cefepime and Nosocomial InfectionsRespiratory Tract InfectionUrinary Tract InfectionNCT02568800Hospital de Clinicas de Porto Alegre134
已完成
3 期
A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial PneumoniaNosocomial Pneumonia (NP)Ventilator-associated Pneumonia (VAP)NCT01808092Pfizer969
终止
3 期
Ceftazidime-Avibactam Use in Critically Ill Patients With Carbapenem-Resistant Enterobacteriaceae InfectionsCarbapenem-Resistant Enterobacteriaceae InfectionNCT05258851King Faisal Specialist Hospital & Research Center29
进行中（未招募）
1 期
Beta-Lactams (ceftazidime, piperacilline-tazobactam, méropénem) dosing scheme validation in septic hemodialysed patientsepsis in patient undergoing dialysis for renal insufficiencyMedDRA version: 18.0Level: HLTClassification code 10040054Term: Sepsis, bacteraemia, viraemia and fungaemia NECSystem Organ Class: 100000004862MedDRA version: 18.0Level: LLTClassification code 10012347Term: Dependence on renal dialysisSystem Organ Class: 100000004869EUCTR2015-001809-14-BEHopital Erasme