Clinical investigation of the effectiveness of different mouth rinses in Covid-19-Patients
- Conditions
- COVID-19
- Registration Number
- DRKS00023725
- Lead Sponsor
- niversität Witten/Herdecke Fakultät für Gesundheit (Department für Zahn-, Mund- und Kieferheilkunde)Lehrstuhl für Zahnerhaltung und Präventive Zahnmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Age: 18-80 years
- Positive, confirmed disease with Covid-19
- Good general condition of the patient
- No elevated temperature
- No elevated blood pressure/pulse
- No increased respiratory rate
- No medication intake
- Presentation of the consent form of the Subject
Exclusion Criteria
- severe general illness
- Subjects with physical and/or mental disabilities mental disabilities with limited manual and cognitive abilities and therefore no comparability possible
- Allergic reactions to the substances used in the study (e.g. hydrogen peroxide)
- alcohol abuse
- Lack of compliance, so that it cannot be ensured that the patients* comply with the study protocol.
- Pregnancy and lactation
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The aim of this study is to determine the virus detection in the throat, using polymerase chain reaction (PCR), in SARS-CoV-2 patients after using the four different mouthwashes with different concentrations and residence time in the mouth.
- Secondary Outcome Measures
Name Time Method The second goal is to find out a correlation of the viral load, between the saliva-NaCl mixture (rinsing with NaCl) and the throat swab.