Effect of prophylactic fibrinogen on post operative bleeding in coronary artery bypass graft surgery
Not Applicable
- Conditions
- Hemorrhage.Hemorrhage, not elsewhere classified
- Registration Number
- IRCT201011085140N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
All candidates for first time elective coronary artery bypass graft surgery. Exclusion criteria: 1-Previously diagnosed hematologic or liver disease, 2-uncontrolled or insulin dependent diabetic mellitus, 3-pregnancy, 4-unstable angina, 5-serum creatinine > 130 µmol/L, 6-left ventricular ejection fraction of less than 35% prior to surgery, 7-serum fibrinogen levels of more than 3/5 g/L.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Volume of postoperative hemorrhage. Timepoint: 0,12,24h after surgery. Method of measurement: overall chest tube drainage during the first 24 hour postoperative hours and was recorded by a pre-trained intensive care unit nurse.
- Secondary Outcome Measures
Name Time Method Transfusion of blood products. Timepoint: first 24 hours post surgery. Method of measurement: The amount of transfused red pack cells, fresh frozen plasma, and platelets during the first 24 hour post-surgery.