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The Effects of Attentional Filter Training on Working Memory

Not Applicable
Completed
Conditions
Cognitive Decline
Healthy
Age-related Cognitive Decline
Interventions
Behavioral: filter training
Behavioral: memory training
Other: no training (control)
Registration Number
NCT03228446
Lead Sponsor
German Center for Neurodegenerative Diseases (DZNE)
Brief Summary

The investigators are interested in how attentional filter training/ distractor inhibition training could influence cognitive functions like working memory, executive control, problem solving, decision making and attentional control.

Detailed Description

Two different computer based trainings were applied: an attentional filter training and a working memory training.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • right-hander
  • aged between 18-30 or 60-80years
Exclusion Criteria
  • severe visual impairments (e.g. dyschromatopsia, very low vision)
  • diseases or medication that might impair test performance
  • Montreal Cognitive Assessment Score (MoCA) < 26 points

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Young subjectsfilter trainingWorking memory training \& attentional filter training for participants (18-30 years)
Old subjectsmemory trainingWorking memory training, attentional filter training and no training (control) for participants (60-80 years)
Young subjectsmemory trainingWorking memory training \& attentional filter training for participants (18-30 years)
Old subjectsno training (control)Working memory training, attentional filter training and no training (control) for participants (60-80 years)
Old subjectsfilter trainingWorking memory training, attentional filter training and no training (control) for participants (60-80 years)
Primary Outcome Measures
NameTimeMethod
Improvements in test performance45min pre / post

Working memory and filtering performance (in %), effects of distractor interference and reaction times for trials with and without distractors with 4, 5 \& 6 targets

Secondary Outcome Measures
NameTimeMethod
Reaction times45min pre / post

Reaction times in each condition

Memory from TAP (Test battery of Attentional Performance)45min pre / post

Working Memory (n-back)

Attention from TAP (Test battery of Attentional Performance)45min pre / post

divided attention, Go-NoGo, Flexibility, Incompatibility, Visual scanning

Performance in repeating numbers10min pre / post

Repeating numbers in forward \& backward conditions

Rey Complex Figure Test30min pre / post

Copying complex figures and reproduce it from memory

Subtest from CANTAB (Cambridge Neuropsychological Test Automated Battery)10min pre / post

Spatial Span Test

Iowa Gambling Task5min on each training day (1-5)

Decision making

Daily Questionnaires2min on each training day (1-5)

Assessing external circumstances of daily influences

Memory performance with distractors among different setsizes45min pre / post

Working memory performance (in %) for trials with 4, 5 \& 6 targets and distractors and averaged performance for all conditions with distractors

Filtering performance with distractors among different setsizes45min pre / post

Filtering performance (in %) for trials with 4, 5 \& 6 targets and distractors and averaged performance for all conditions with distractors

Memory performance without distractors among different setsizes45min pre / post

Working memory performance (in %) for trials with 4, 5 \& 6 targets and averaged performance for all conditions without distractors

Filtering performance without distractors among different setsizes45min pre / post

Filtering performance (in %) for trials with 4, 5 \& 6 targets and averaged performance for all conditions without distractors

Values of distractor inhibition45min pre / post

Distractor inhibition (DIIN) = Mean of conditions without distractors - Mean of conditions with distractors

Trial Locations

Locations (1)

DZNE

🇩🇪

Magdeburg, Sachsen-Anhalt, Germany

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