Use OF VISHTINDUKA TAILA & VATARI GUGGULU IN GRIDHRASI (SCIATICA)
- Conditions
- Acquired deformity of musculoskeletal system, unspecified. Ayurveda Condition: GRUDHRASI,
- Registration Number
- CTRI/2025/04/085932
- Lead Sponsor
- Department of Agadtantra Evum Vidhi Ayurved Shri NPA Govt Ayurvedic College GE road Raipur
- Brief Summary
Ayurveda,an ancient science of life, focuses on maintaining balance for health andlongevity. It divides health principles into eight branches, one of which is *AgadTantra*, dealing with poisons and their treatment. Acharya Charak emphasizedthat poisons, when properly prepared, can become medicines, and conversely,even beneficial medicines can become toxic if used incorrectly. A key part ofAyurveda is understanding *Tridosha*—the balance of Vata, Pitta, andKapha. When these energies are in equilibrium, health prevails; imbalances leadto diseases.
Onesuch disease is *Gridhrasi*, similar to sciatica in modern medicine,characterized by pain, stiffness, and restricted leg movement. It arises fromimbalances in Vata, and in some cases, also Kapha. Sciatica is a commoncondition, caused by issues like poor posture, prolonged sitting, and obesity.It affects many individuals, especially those aged 30-50, and often leads topain, disability, and discomfort.
InAyurveda, treatments such as *Vishtinduka Taila* (derived from *Strychnosnux-vomica*, a poisonous plant) and *Vatari Guggulu* (a herbal remedy)are used for conditions like Gridhrasi. These treatments have properties likepain relief, anti-inflammatory, and nerve tonic effects. However, the toxicpotential of these treatments, especially from the use of Vishtinduka, requirescareful evaluation. Toxicity studies in animals are essential to ensure theirsafety for human use.
Thisstudy aims to evaluate the safety of Vishtinduka Taila through dermal exposurein rats and its clinical effectiveness in treating Gridhrasi. Additionally,Vatari Guggulu’s non-toxic profile has already been established. The ultimategoal is to find an effective, safe treatment for sciatica, using traditionalAyurvedic remedies.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
1 Patient between the age of 18-60 years randomly included in study 2 Sex – both male and female 3 Duration of illness – upto 1 year 4 Tenderness of the Sciatic Nerve course 5 Severe pain on squatting 6 Radiating pain, starting from the gluteal region towards the foot 7 Sensory change 8 Non-involvement of Urinary Bladder and Rectum 9 Positive straight leg raising sign.
1 Age below 20 years and above 70 years 2 Duration of disease more than 1 years 3 Monoplegia 4 Paraplegia 5 Hip joint arthritis 6 TB Spine/Hip 7 Pelvic pathology 8 Traumatic lesion in lumbo – sacral region.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 2 Ruka 30 Days 11 Mukhapraseka 30 Days OBJECTIVE PARAMETERS – 30 Days 3 Bowstring’s test 30 Days 4 Sitting time 30 Days 4 Muhurmuhu spandanam 30 Days 5 Sakthikshepana nigrahat 30 Days 8 Gaurava 30 Days 13 Staimitya 30 Days 6 Dehasya pravakrata 30 Days 9 Aruchi 30 Days 12 Bhaktadwesh 30 Days 1 Lasegue’s test 30 Days 2 Bragard’s test 30 Days 5 Standing time 30 Days 6 Walking distance 30 Days 10 Vahnimardavam (Agnimandhya) 30 Days Subjective parameter 30 Days 1 Stambha 30 Days 3 Toda 30 Days 7 Tandra 30 Days
- Secondary Outcome Measures
Name Time Method Effectiveness of Vishatinduka Taila & Vatari Guggulu in reducing pain associated with sciatica. Improvements in patient’s quality of life due to reduced pain & increased mobility would be an important outcome 30 Days
Trial Locations
- Locations (1)
Shri Khudadad Dungaji Govt. Ayurvedic Hospital Raipur Chhattisgarh 492010
🇮🇳Raipur, CHHATTISGARH, India
Shri Khudadad Dungaji Govt. Ayurvedic Hospital Raipur Chhattisgarh 492010🇮🇳Raipur, CHHATTISGARH, IndiaDr Rupali YadavPrincipal investigator7974149684rupaliyadavbsp1995@gmail.com