Comparison of Sucralfate and Nifedipine cream with Nifedipine alone in the management of Fissure in Ano.
Not Applicable
- Conditions
- Health Condition 1: K601- Chronic anal fissure
- Registration Number
- CTRI/2023/07/055028
- Lead Sponsor
- JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Inclusion criteria
Patients coming to JIPMER general surgery OPD and casualty during the study period fulfilling the following criteria
All patients with Chronic fissure in ano (symptoms >6 weeks, fissure with hypertrophied anal papilla and sentinel pile) above 18yrs age
Exclusion Criteria
1.Patients with cardiovascular illness, heart failure, diabetes
2.Patient having secondary causes if fissure such as HIV/AIDS, inflammatory bowel disease, malignancy and dermatological conditions like psoriasis.
3.Patients taking Diltiazem or Nifedipine drug.
4.Patients on chronic use of analgesics such as for head-ache
5.Patient denying consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effectiveness of Topical sucralfate with <br/ ><br> <br/ ><br>standard of care and standard of care alone in relieving pain of patients with Chronic Fissure in Ano at 2 weeks. <br/ ><br>(Drugs used in standard of care are 0.3% Nifedipine and 1.5 % Lignocaine cream) <br/ ><br>Timepoint: 2 WEEKS <br/ ><br>
- Secondary Outcome Measures
Name Time Method To compare the healing in both the groups <br/ ><br> <br/ ><br>To compare the anal bleeding in both the groupsTimepoint: 2 weeks