Effect of Ranitidine and Sucralfate on the incidence of ventilator-associated pneumonia
Not Applicable
- Conditions
- ventilator-associated pneumon.Other postprocedural respiratory disorders
- Registration Number
- IRCT2017080835577N1
- Lead Sponsor
- vice chancellor for research & technology of Rafsanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 148
Inclusion Criteria
patients aged between 15 and 75 years old ; men or women ; has the sofa score 4 to 10 at the time of admission; require intubation for more than 48 hours.
Exclusion criteria : History of recent pulmonary infection or gastrointestinal bleeding; Early discharge of ICU ; Extubation less than 48 hours ; Patients Has any immunodeficiency.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of serum ESR. Timepoint: Daily for 6 days. Method of measurement: Serum ESR test.;Amount of serum white blood cells. Timepoint: Daily for 6 days. Method of measurement: Cell blood count test.;Amount of arterial oxygen concentration. Timepoint: Daily for 6 days. Method of measurement: Arterial blood gas.;Type of Nasotracheal discharge. Timepoint: Daily for 6 days. Method of measurement: Nasotracheal discharge culture.;Incidence of VAP. Timepoint: Daily for 6 days. Method of measurement: culture of discharge.
- Secondary Outcome Measures
Name Time Method Amount of body temperature. Timepoint: Every 12 hours for 6 days. Method of measurement: With sub axillary thermometer.;Amount of serum cratinin. Timepoint: Daily for 10 days. Method of measurement: Serum cratinin test.