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The comparison of the efficacy of two therapeutic regimens in the treatment of gastroesophageal reflux disease in term neonates.

Not Applicable
Recruiting
Conditions
Gastroesophageal Reflux.
Gastro-oesophageal reflux disease
Registration Number
IRCT20160827029535N5
Lead Sponsor
Bahrami hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
90
Inclusion Criteria

Healthy term neonates aged 1–30days with GERD .

Exclusion Criteria

Healthy term neonates aged 1–30days with GERD not responding to conservative therapies including antireflux positioning, milk thickening, hypoallergic regimens and monotherapy

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The comparison of ranitidine with esomeprazole in neonatal GERD. Timepoint: One week and one month after using each drug. Method of measurement: using (I-GERDQ-R) and related scoring.
Secondary Outcome Measures
NameTimeMethod
The side effects of each drug. Timepoint: After one week and one month of administering. Method of measurement: Clinical manifestations.
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