Ranitidine and pantoprazole in prevention of stress ulcer
Not Applicable
- Conditions
- stress ulcer.Gastric ulcer
- Registration Number
- IRCT201104134578N2
- Lead Sponsor
- Hamedan University of Medical Sciences-vice chancellor for research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
Patients who required mechanical ventilation, Age more than 18 years old, Admission to the ICU, APACHE SCORE II less than 25, Admission at least 24 hour in ICU, Patients with suctionable secretion, No GI bleeding at the beginning of study
Exclusion criteria: History of GI bleeding, liver or kidney insufficiency, History of corticosteroids or NSAIDs usage, Gastric PH more than 4 before beginning of prophylaxis
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gastric PH. Timepoint: Before intervention, every 8 houres after intervention for two next days. Method of measurement: The level of gastric PH which is measured by AZ8685 PH metery instrument.
- Secondary Outcome Measures
Name Time Method GI bleeding. Timepoint: Daily. Method of measurement: Evaluating the secretion which lavaged from the patient NG tube to the end of admission in the ICU.