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临床试验/NCT01615276
NCT01615276已完成不适用

The Effect of Neuromuscular Electrical Stimulation on Post-prandial Muscle Protein Accretion in Healthy Elderly Men

Maastricht University Medical Center1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2012年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
1
主要终点
Tracer enrichment in the muscle biopsy

研究概览

简要总结

In the present study, the effect of a bolus of intrinsically labeled milk directly after one-legged NMES will be studied.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
65 Years 至 85 Years(Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Age 65 - 85 years
  • 18.5 < BMI < 30 kg∙m2

排除标准

  • Type II diabetes
  • All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders, paralysis, hip/knee surgery).
  • Use of anticoagulants, blood diseases, allergy for lidocaine
  • Use of NSAIDs and acetylsalicylic acid
  • Patients suffering from PKU (Phenylketonuria)
  • Presence of implantable cardioverter defibrillator and/or pacemaker
  • Performed regular resistance type exercise in the past 6 months

结局指标

主要结局

Tracer enrichment in the muscle biopsy

时间窗: 4 hours after protein ingestion

次要结局

  • Fractional synthetic rate (FSR)(0-4 hours after protein ingestion)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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