NCT01615276已完成不适用
The Effect of Neuromuscular Electrical Stimulation on Post-prandial Muscle Protein Accretion in Healthy Elderly Men
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Tracer enrichment in the muscle biopsy
研究概览
简要总结
In the present study, the effect of a bolus of intrinsically labeled milk directly after one-legged NMES will be studied.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 85 Years（Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age 65 - 85 years
- •18.5 < BMI < 30 kg∙m2
排除标准
- •Type II diabetes
- •All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders, paralysis, hip/knee surgery).
- •Use of anticoagulants, blood diseases, allergy for lidocaine
- •Use of NSAIDs and acetylsalicylic acid
- •Patients suffering from PKU (Phenylketonuria)
- •Presence of implantable cardioverter defibrillator and/or pacemaker
- •Performed regular resistance type exercise in the past 6 months
研究组 & 干预措施
Protein ingestion
Placebo Comparator
Protein ingestion directly after the contralateral leg received NMES
干预措施: No Enraf Nonius Tensmed S84 for Neuromuscular electrical stimulation (NMES) NMES (Device)
Protein ingestion after NMES
Experimental
Ingestion of intrinsically labeled protein, directly after one hour of Neuromuscular electrical stimulation (NMES)
干预措施: Enraf Nonius Tensmed S84 for Neuromuscular electrical stimulation (NMES) (Device)
结局指标
主要结局
Tracer enrichment in the muscle biopsy
时间窗: 4 hours after protein ingestion
次要结局
- Fractional synthetic rate (FSR)(0-4 hours after protein ingestion)
研究者
研究点 (1)
Loading locations...
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